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KMID : 1134820110400081107
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Journal of the Korean Society of Food Science and Nutrition
2011 Volume.40 No. 8 p.1107 ~ p.1112
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Protective Effects of Food Including Hovenia dulcis on Acute Alcohol Intoxication
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Choi Geun-Ho
Kim Jong-Gwan
Kwon Seoung-Taek
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Abstract
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Over-consumption of alcohol leads to many side-effects such as malnutrition, liver disease, and neuronal disorders and many investigators have tired to identify methods for preventing the side-effects of drinking. In this study, we demonstrated the protective effect of a new food component, SAC-1, containing Hovenia dulcis Thumb and Lonicera caerulea Thumb extract against the side-effects of drinking. We observed that blood alcohol concentration, glutamic oxaloacetate transaminase, lipid peroxidation, and total glutathione level decreased significantly in plasma and liver of mice fed the SAC-1 extract before alcohol intoxication. In particular, SAC-1 had more of a protective effect than that of Hovenia dulcis Thumb extract alone. These results suggest that SAC-1 should further be developed to treat alcohol detoxification and stimulate antioxidative potentials.
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KEYWORD
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alcohol intoxication, Hovenia dulcis, functional food, liver, alcohol toxicity
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